O-Xylene

O-Xylene

SCHEMBL871453

Cc1ccccc1C.F.F.F.F.F.F

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.91
ACHE P22303 3/20 0.91
ALDH1A1 P00352 4/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA7 P43166 2/20 0.53
CA9 Q16790 2/20 0.53
CYP1A2 P05177 2/20 0.50
CYP2A6 P11509 2/20 0.50
CYP3A4 P08684 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
LMNA P02545 1/20 0.47
ALOX12 P18054 1/20 0.47
MAPT P10636 1/20 0.43
HTT P42858 1/20 0.43
ESR1 P03372 1/20 0.43
TAAR1 Q96RJ0 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TRPA1 O75762 1/20 0.40
CD44 P16070 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL28515699 1.00 TSHR (0.91) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL27308414 1.00
O-Xylene SCHEMBL28200895 0.96 TSHR (0.83) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL11035539 0.95 TSHR (1.00) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL8216257 0.95 TSHR (1.00) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL2854068 0.95
O-Xylene SCHEMBL29385454 0.95
O-Xylene SCHEMBL10522915 0.95 TSHR (1.00) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL772 0.95
O-Xylene SCHEMBL11034038 0.95 TSHR (1.00) TSHRACHEALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 377 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3088487-B1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND DAIKIN IND LTD (JP) 2021-05-05 EP claimed
US-10703932-B2 Surface treating agent including perfluoro(poly)ether-group-containing silane compound DAIKIN INDUSTRIES, LTD. (JP) 2020-07-07 US claimed
WO-2020138417-A1 CURABLE SILICONE COMPOSITION, RELEASE COATING AGENT COMPRISING SAID COMPOSITION, RELEASE FILM OBTAINED USING SAID RELEASE COATING AGENT, AND LAYERED PRODUCT INCLUDING SAID RELEASE FILM ダウ・東レ株式会社 2020-07-02 WO claimed
WO-2020138399-A1 CURABLE SILICONE COMPOSITION, RELEASE COATING AGENT COMPRISING SAID COMPOSITION, RELEASE FILM OBTAINED USING SAID RELEASE COATING AGENT, AND LAYERED PRODUCT INCLUDING SAID RELEASE FILM ダウ・東レ株式会社 2020-07-02 WO claimed
EP-3037456-B1 BIFUNCTIONAL COMPOUND CONTAINING PERFLUORO(POLY)ETHER GROUP, COMPOSITION WHICH CONTAINS BIFUNCTIONAL COMPOUND CONTAINING PERFLUORO(POLY)ETHER GROUP, AND METHODS FOR PRODUCING SAID COMPOUND AND SAID COMPOSITION DAIKIN IND LTD (JP) 2019-05-08 EP claimed
US-20160340544-A1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND DAIKIN INDUSTRIES, LTD. (JP) 2016-11-24 US claimed
EP-3088487-A1 SURFACE TREATING AGENT INCLUDING PERFLUORO(POLY)ETHER-GROUP-CONTAINING SILANE COMPOUND Daikin Industries, Ltd. (JP) 2016-11-02 EP claimed
EP-3037456-A1 BIFUNCTIONAL COMPOUND CONTAINING PERFLUORO(POLY)ETHER GROUP, COMPOSITION WHICH CONTAINS BIFUNCTIONAL COMPOUND CONTAINING PERFLUORO(POLY)ETHER GROUP, AND METHODS FOR PRODUCING SAID COMPOUND AND SAID COMPOSITION Daikin Industries, Ltd. (JP) 2016-06-29 EP claimed
CN-105683248-A Bifunctional compound containing perfluoro(poly)ether group, composition which contains bifunctional compound containing perfluoro(poly)ether group, and methods for producing said compound and said composition 大金工业株式会社 2016-06-15 CN claimed
US-3931454-A Printed circuit board and method of preparing it WESTINGHOUSE ELECTRIC CORPORATION (US) 1976-01-06 US claimed
JP-62200336-A None JP disclosed
JP-6122862-A None JP disclosed
JP-5112584-A None JP disclosed
JP-6093212-A None JP disclosed
US-12617969-B2 Layered product DAIKIN INDUSTRIES, LTD. (JP) 2026-05-05 US disclosed
US-3993833-A FLUOROALIPHATIC FOAM STABILIZER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-11-23 US disclosed
US-3972856-A LOW TEMPERATURE FLEXIBLE MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1976-08-03 US disclosed
US-3949136-A OIL REPELLENTS, WATERPROOFING TEXTILES CIBA-GEIGY AG (CH) 1976-04-06 US disclosed
US-3947257-A BENZOTRIFLUORIDE FUEL ADDITIVE FOR INTERNAL COMBUSTION ENGINES RAYCHEM CORPORATION (US) 1976-03-30 US disclosed
US-3931454-A Printed circuit board and method of preparing it WESTINGHOUSE ELECTRIC CORPORATION (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617969-B2 Layered product CDH1, PF4, ITGB4 TSHR 2003/4885ACHE 4142/4885ALDH1A1 1258/4885
US-10703932-B2 Surface treating agent including perfluoro(poly)ether-group-containing silane compound FRG1, AFF1, F11 TSHR 183/4885ACHE 4608/4885ALDH1A1 1578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.