Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8714176 | 0.88 | MAOB (0.43) | KIF11KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL8719238 | 0.87 | TPH1 (0.39) | KIF11HDAC1NPC1LMNARAB9A | |
| SCHEMBL8713560 | 0.86 | KIF11 (0.42) | KIF11NPC1LMNARAB9ACYP1A2 | |
| SCHEMBL8714644 | 0.86 | KIF11 (0.44) | KIF11PKM | |
| SCHEMBL8713771 | 0.85 | ADRB2 (0.45) | KIF11KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL8713274 | 0.85 | RAB9A (0.50) | KIF11KMT2ANPC1LMNARAB9A | |
| SCHEMBL8714279 | 0.83 | KIF11 (0.40) | KIF11CYP1A2CYP2C19EPHX2PKM | |
| SCHEMBL8713872 | 0.81 | ESR1 (0.42) | KIF11PKM | |
| SCHEMBL8716173 | 0.81 | KIF11 (0.40) | KIF11CYP1A2CYP2C19PKM | |
| SCHEMBL8717072 | 0.81 | KIF11 (0.40) | KIF11KMT2ANPSR1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |