Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.45 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8717166 | 0.90 | LMNA (0.59) | RAB9ALMNACYP1A2CYP2C19MEN1 | |
| SCHEMBL8713771 | 0.87 | ADRB2 (0.45) | RAB9ACYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL8714644 | 0.85 | KIF11 (0.44) | KIF11PTGER4PTGER2 | |
| SCHEMBL8713377 | 0.85 | KIF11 (0.39) | RAB9ALMNACYP1A2CYP2C19MEN1 | |
| SCHEMBL8713560 | 0.83 | KIF11 (0.42) | RAB9ALMNACYP1A2CYP2C19EPHX2 | |
| SCHEMBL8714176 | 0.83 | MAOB (0.43) | RAB9ACYP1A2CYP2C19MEN1KMT2A | |
| SCHEMBL8714910 | 0.81 | KIF11 (0.43) | KIF11 | |
| SCHEMBL8714279 | 0.81 | KIF11 (0.40) | CYP1A2CYP2C19EPHX2NR1H4CYP2D6 | |
| SCHEMBL8713872 | 0.79 | ESR1 (0.42) | KIF11 | |
| SCHEMBL8716173 | 0.79 | KIF11 (0.40) | CYP1A2CYP2C19CYP2D6CYP2C9KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |