Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8718127 | 0.91 | TAOK1 (0.54) | KMT2AMEN1MAPTALDH1A1CYP1A2 | |
| SCHEMBL8714614 | 0.84 | MEN1 (0.52) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL8718456 | 0.79 | ALDH1A1 (0.48) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL8714945 | 0.78 | KMT2A (0.57) | KMT2AMEN1MAPTALDH1A1CYP1A2 | |
| SCHEMBL8717618 | 0.78 | KMT2A (0.41) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL8713944 | 0.77 | NPC1 (0.41) | KMT2AALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL8715313 | 0.75 | ALDH1A1 (0.47) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL8718493 | 0.74 | ALDH1A1 (0.42) | MAPTALDH1A1TDP1LMNAL3MBTL1 | |
| SCHEMBL7343810 | 0.73 | ALDH1A1 (0.64) | KMT2AMEN1MAPTALDH1A1CYP1A2 | |
| SCHEMBL8715144 | 0.72 | CFD (0.39) | LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |