Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713944 | 0.87 | NPC1 (0.41) | KMT2ALMNAALDH1A1POLBTP53 | |
| SCHEMBL8716877 | 0.83 | POLB (0.45) | HTTLMNAALDH1A1POLBTP53 | |
| SCHEMBL8718456 | 0.79 | ALDH1A1 (0.48) | KMT2ALMNAALDH1A1MEN1MAPK1 | |
| SCHEMBL8717614 | 0.78 | KMT2A (0.41) | KMT2AGAAHTTLMNAALDH1A1 | |
| SCHEMBL8714949 | 0.78 | KMT2A (0.54) | KMT2AHTTLMNAALDH1A1MEN1 | |
| SCHEMBL8715144 | 0.78 | CFD (0.39) | LMNATP53 | |
| SCHEMBL8714614 | 0.77 | MEN1 (0.52) | KMT2AHTTLMNAALDH1A1POLB | |
| SCHEMBL8715313 | 0.75 | ALDH1A1 (0.47) | KMT2ALMNAALDH1A1POLBMEN1 | |
| SCHEMBL8718493 | 0.74 | ALDH1A1 (0.42) | HTTLMNAALDH1A1TP53HPGD | |
| SCHEMBL8718127 | 0.73 | TAOK1 (0.54) | KMT2AGAAHTTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753677-A | Benzoheterocyclic compounds | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |