Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7836565 | 0.80 | MMP1 (0.38) | PTPN1 | |
| SCHEMBL8002993 | 0.77 | CYP1A2 (0.34) | TSHRMEN1KMT2A | |
| SCHEMBL4995125 | 0.75 | MMP8 (0.40) | MEN1KMT2A | |
| SCHEMBL29170737 | 0.72 | PTPN1 (0.39) | PTPN1TSHRMEN1KMT2A | |
| SCHEMBL4347216 | 0.72 | — | — | |
| SCHEMBL1564814 | 0.72 | PTPN1 (0.39) | PTPN1TSHRMEN1KMT2A | |
| SCHEMBL11118056 | 0.72 | FDPS (0.33) | — | |
| SCHEMBL11529906 | 0.71 | PTPN1 (0.41) | PTPN1TSHRMEN1KMT2A | |
| SCHEMBL235499 | 0.69 | TSHR (0.46) | PTPN1TSHRMEN1KMT2AHCAR2 | |
| SCHEMBL2721087 | 0.67 | PTPN1 (0.44) | PTPN1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830902-A | SQUALENE SYNTHASE INHIBITOR | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1998-11-03 | — | — | US | disclosed |
| EP-0812840-A1 | NOVEL QUINUCLIDINE DERIVATIVES HAVING TRICYCLIC FUSED HETERO RING | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-12-17 | — | — | EP | disclosed |