Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 3/20 | 0.37 |
| ▸ | CTSS | P25774 | 3/20 | 0.36 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6320315 | 0.83 | TRPM8 (0.35) | KLKB1KLK1CTSBCTSSCTSL | |
| SCHEMBL6325998 | 0.79 | ADAM17 (0.36) | NPC1LMNAHPGDRAB9ACTSS | |
| SCHEMBL8206197 | 0.75 | RAB9A (0.38) | NPC1LMNARAB9AKLKB1KLK1 | |
| SCHEMBL6324203 | 0.74 | GHSR (0.35) | LMNACTSSMMP1MMP3ADAM17 | |
| SCHEMBL6318955 | 0.74 | CTSC (0.35) | LMNAKLKB1KLK1CTSSMMP1 | |
| SCHEMBL6324114 | 0.74 | LOXL2 (0.39) | KLKB1KLK1CTSBCTSSCTSL | |
| SCHEMBL6317903 | 0.73 | GHSR (0.44) | KLKB1KLK1HPGDSALDH1A1ADAM17 | |
| SCHEMBL6318111 | 0.73 | GHSR (0.53) | CTSBCTSSADAM17CTSC | |
| SCHEMBL6318119 | 0.73 | GHSR (0.53) | CTSBCTSSADAM17CTSC | |
| SCHEMBL8525046 | 0.72 | CTSL (0.51) | KLKB1KLK1CTSSCTSLMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869974-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1998-10-14 | — | — | EP | claimed |