Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12873561 | 0.79 | TSHR (0.34) | TSHRKCNA5 | |
| SCHEMBL4500673 | 0.76 | CYP2D6 (0.47) | TSHRHSD17B10KDM4EALDH1A1KCNA5 | |
| SCHEMBL4269410 | 0.76 | LMNA (0.40) | HSD17B10ALDH1A1 | |
| SCHEMBL6462366 | 0.73 | TAAR1 (0.41) | — | |
| SCHEMBL3225194 | 0.70 | LMNA (0.55) | TSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL22073007 | 0.69 | MMP2 (0.46) | TSHRHSD17B10KDM4EALDH1A1 | |
| Methyl Alcohol SCHEMBL8463683 | 0.68 | LMNA (0.52) | TSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL8716232 | 0.67 | FFAR2 (0.42) | TSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL17697838 | 0.67 | LMNA (0.33) | — | |
| SCHEMBL28266841 | 0.67 | APLNR (0.43) | TSHRAPLNRKDM4EALDH1A1KCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756525-A | USING A THIAZOLIDINEDIONE COMPOUND | BEECHAM GROUP PLC (GB) | 1998-05-26 | — | — | US | disclosed |