Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 3/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 3/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330324 | 0.81 | MTNR1B (0.39) | MTNR1AMTNR1BRAB9ANQO2 | |
| SCHEMBL8335532 | 0.80 | TDP1 (0.41) | MTNR1AMTNR1BNPC1RAB9AMEN1 | |
| SCHEMBL8334169 | 0.80 | MTNR1B (0.38) | MTNR1AMTNR1BRAB9ANQO2POLB | |
| SCHEMBL8335539 | 0.79 | TDP1 (0.38) | FFAR1MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL8097742 | 0.77 | MTNR1A (0.52) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8097744 | 0.77 | MTNR1A (0.52) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8333896 | 0.76 | MAPT (0.44) | MTNR1AMTNR1BNPC1RAB9ANQO2 | |
| SCHEMBL8329351 | 0.75 | HTR2A (0.47) | MTNR1AMTNR1B | |
| SCHEMBL8332882 | 0.75 | HTR2A (0.47) | MTNR1AMTNR1B | |
| SCHEMBL8332746 | 0.74 | KDM1A (0.38) | FFAR1ADORA3NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753709-A | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-19 | — | — | US | disclosed |