Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716391 | 0.86 | CTSD (0.43) | KMT2ASIGMAR1L3MBTL1OPRK1CHRM2 | |
| SCHEMBL8715002 | 0.77 | SIGMAR1 (0.51) | SIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL8713086 | 0.74 | SLC6A4 (0.47) | SIGMAR1SLC6A4 | |
| SCHEMBL8713649 | 0.72 | OPRD1 (0.43) | KMT2ASIGMAR1SLC6A4OPRM1OPRD1 | |
| SCHEMBL1838692 | 0.72 | NPC1 (0.73) | KMT2ANPC1TDP1L3MBTL1MEN1 | |
| SCHEMBL8713364 | 0.72 | TDP1 (0.44) | KMT2ASIGMAR1TDP1SLC6A4MEN1 | |
| SCHEMBL8718000 | 0.71 | SIGMAR1 (0.46) | KMT2ASIGMAR1SLC6A4OPRD1MEN1 | |
| Hydrochloric Acid SCHEMBL3086821 | 0.71 | NPC1 (0.71) | KMT2ANPC1TDP1L3MBTL1MEN1 | |
| SCHEMBL8716281 | 0.70 | HRH4 (0.49) | — | |
| SCHEMBL28208386 | 0.70 | ALOX5 (0.57) | KMT2ATDP1L3MBTL1ALOX5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822939-A1 | CYCLIC PENTAPEPTIDE LH-RH RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 1998-02-11 | — | — | EP | disclosed |
| WO-1996034012-A1 | CYCLIC PENTAPEPTIDE LH-RH RECEPTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-31 | — | — | WO | disclosed |