Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 10/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8715002 | 0.79 | SIGMAR1 (0.51) | OPRD1SIGMAR1OPRM1OPRK1POLB | |
| SCHEMBL8716391 | 0.74 | CTSD (0.43) | KMT2ASIGMAR1OPRK1ALDH1A1TSHR | |
| SCHEMBL8717153 | 0.72 | KMT2A (0.42) | OPRD1MEN1KMT2ASIGMAR1OPRM1 | |
| Diphenamide SCHEMBL572567 | 0.70 | OPRM1 (0.49) | OPRD1MEN1KMT2AOPRM1OPRK1 | |
| SCHEMBL1677888 | 0.70 | TSHR (0.56) | OPRD1MEN1KMT2ASIGMAR1POLB | |
| SCHEMBL27705053 | 0.70 | OPRD1 (0.47) | OPRD1MEN1KMT2ASIGMAR1OPRM1 | |
| SCHEMBL16857496 | 0.69 | CA2 (0.34) | — | |
| SCHEMBL8713369 | 0.68 | OPRD1 (0.49) | OPRD1MEN1KMT2AOPRM1ALDH1A1 | |
| SCHEMBL8716688 | 0.68 | HTR3E (0.50) | KMT2APOLBALDH1A1LMNA | |
| SCHEMBL1961974 | 0.68 | CA2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822939-A1 | CYCLIC PENTAPEPTIDE LH-RH RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 1998-02-11 | — | — | EP | disclosed |
| WO-1996034012-A1 | CYCLIC PENTAPEPTIDE LH-RH RECEPTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-10-31 | — | — | WO | disclosed |