Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719953 | 0.87 | ALDH1A1 (0.42) | MEN1KMT2A | |
| SCHEMBL8716993 | 0.85 | ALDH1A1 (0.40) | OPRK1CYP3A4 | |
| SCHEMBL8717616 | 0.85 | ALDH1A1 (0.37) | OPRK1 | |
| SCHEMBL8717430 | 0.85 | ALDH1A1 (0.37) | OPRK1CNR2 | |
| SCHEMBL6425483 | 0.83 | KCNA3 (0.44) | OPRK1 | |
| SCHEMBL8719819 | 0.82 | OPRK1 (0.41) | OPRK1MEN1KMT2A | |
| SCHEMBL8719917 | 0.77 | OPRK1 (0.42) | OPRK1MEN1KMT2A | |
| SCHEMBL13650590 | 0.75 | ALDH1A1 (0.57) | OPRK1MEN1KMT2A | |
| SCHEMBL22488317 | 0.75 | ALDH1A1 (0.57) | OPRK1MEN1KMT2A | |
| SCHEMBL22488321 | 0.75 | ALDH1A1 (0.57) | OPRK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569802-B1 | Arylacetamides | MERCK PATENT GMBH (DE) | 1998-07-15 | — | — | EP | disclosed |
| EP-0569802-A1 | Arylacetamides | MERCK PATENT GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |