Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.40 |
| ▸ | HRH2 | P25021 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8720345 | 0.87 | OPRK1 (0.42) | MEN1KMT2A | |
| SCHEMBL8717430 | 0.83 | ALDH1A1 (0.37) | ALDH1A1HRH1SMN1; SMN2 | |
| SCHEMBL8716993 | 0.83 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL8717616 | 0.83 | ALDH1A1 (0.37) | ALDH1A1LTA4H | |
| SCHEMBL6425483 | 0.81 | KCNA3 (0.44) | ALDH1A1CYP2D6LTA4H | |
| SCHEMBL8719819 | 0.72 | OPRK1 (0.41) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL24302920 | 0.72 | HRH3 (0.63) | MEN1KMT2ALTA4HHRH3HRH2 | |
| SCHEMBL8719917 | 0.70 | OPRK1 (0.42) | MEN1KMT2ALTA4HMAPT | |
| SCHEMBL8719943 | 0.69 | LTA4H (0.44) | ALDH1A1MEN1CYP2D6RAB9AKMT2A | |
| SCHEMBL8350936 | 0.69 | ALDH1A1 (0.38) | ALDH1A1HRH1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569802-B1 | Arylacetamides | MERCK PATENT GMBH (DE) | 1998-07-15 | — | — | EP | disclosed |
| EP-0569802-A1 | Arylacetamides | MERCK PATENT GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |