Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845301 | 0.92 | PABPC1 (0.51) | PABPC1KDM4EGAALMNARXFP1 | |
| SCHEMBL872930 | 0.88 | GAA (0.52) | PABPC1KDM4EGAALMNAHCRTR2 | |
| SCHEMBL10119551 | 0.88 | DHODH (0.40) | GAAALDH1A1SCN9ASCN3ASCN5A | |
| SCHEMBL872415 | 0.83 | PABPC1 (0.38) | PABPC1KDM4EGAALMNAALDH1A1 | |
| SCHEMBL871971 | 0.83 | PDE5A (0.42) | PABPC1KDM4EGAALMNAHCRTR2 | |
| SCHEMBL874324 | 0.83 | MAPK1 (0.42) | PABPC1GAALMNAALDH1A1MAPK1 | |
| SCHEMBL874313 | 0.82 | MAPK1 (0.50) | GAALMNAALDH1A1TSHRKMT2A | |
| SCHEMBL13272508 | 0.82 | GAA (0.42) | PABPC1KDM4EGAALMNARXFP1 | |
| SCHEMBL872886 | 0.81 | KDM4E (0.52) | PABPC1KDM4EGAALMNAALDH1A1 | |
| SCHEMBL10119636 | 0.81 | CYP2C9 (0.38) | PABPC1ALDH1A1SCN9ASCN3AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |