Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.54 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14447514 | 0.85 | TACR1 (0.64) | TACR1POLBLMNAMAPTSOAT1 | |
| SCHEMBL12863534 | 0.79 | POLB (0.56) | POLBLMNAHDAC1HDAC7HDAC8 | |
| SCHEMBL10027976 | 0.79 | LMNA (0.59) | POLBLMNAMAPTALDH1A1HTT | |
| SCHEMBL19422611 | 0.78 | POLB (0.57) | POLBLMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL12963094 | 0.78 | LMNA (0.57) | POLBLMNAHDAC1HDAC7HDAC8 | |
| SCHEMBL12863539 | 0.78 | S1PR4 (0.54) | HDAC1HDAC7HDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL7207413 | 0.78 | LMNA (0.61) | POLBLMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL19501566 | 0.77 | LMNA (0.54) | POLBLMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL27529524 | 0.77 | PDK1 (0.66) | TACR1HDAC1HDAC7HDAC8HDAC6 | |
| SCHEMBL6206191 | 0.77 | ALDH1A1 (0.69) | LMNAMAPTSOAT1KCNQ2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827869-A | Substituted biphenyl isoxazole sulfonamides | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |