Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.34 |
| ▸ | MPEG1 | Q2M385 | 7/20 | 0.34 |
| ▸ | USP2 | O75604 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27615467 | 0.76 | XIAP (0.48) | XIAPMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL29140682 | 0.71 | XIAP (0.48) | XIAPMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL871824 | 0.64 | XIAP (0.32) | XIAPMAPTALDH1A1HPGDMAPK1 | |
| SCHEMBL13954373 | 0.63 | CES2 (0.53) | MAPTKDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL30003252 | 0.62 | KDM4E (0.38) | XIAPMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL9220665 | 0.62 | XIAP (0.54) | XIAPMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL6618539 | 0.62 | MEN1 (0.38) | MAPTKDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL2536906 | 0.62 | P2RX7 (0.35) | XIAPMAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL5574060 | 0.62 | AURKA (0.34) | MAPTKDM4EALDH1A1HPGDMAPK1 | |
| SCHEMBL169616 | 0.61 | KDM4E (0.43) | XIAPMAPTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928415-A2 | TOPICAL DELIVERY WITH A CARRIER FLUID | Collegium Pharmaceutical, Inc. (US) | 2008-06-11 | — | — | EP | claimed |
| WO-2007022090-A2 | TOPICAL DELIVERY WITH A CARRIER FLUID | COLLEGIUM PHARMACEUTICAL, INC. (US) | 2007-02-22 | — | — | WO | claimed |
| US-20070036731-A1 | Topical Delivery with a Carrier Fluid | COLLEGIUM PHARMACEUTICAL, INC. | 2007-02-15 | — | — | US | claimed |
| EP-3226977-B1 | GLASS COMPOSITES FOR TISSUE AUGMENTATION, BIOMEDICAL AND COSMETIC APPLICATIONS | UNIV RES INST INC AUGUSTA (US) | 2021-06-23 | — | — | EP | disclosed |
| US-20190117828-A1 | Glass Composites for Tissue Augmentation, Biomedical and Cosmetic Applications | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. | 2019-04-25 | — | — | US | disclosed |
| US-10201633-B2 | Glass composites for tissue augmentation, biomedical and cosmetic applications | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. (US) | 2019-02-12 | — | — | US | disclosed |
| US-9920058-B2 | Molecules with potent DHFR binding affinity and antibacterial activity | GEORGIA TECH RESEARCH CORPORATION (US) | 2018-03-20 | — | — | US | disclosed |
| US-20170354755-A1 | Glass Composites for Tissue Augmentation, Biomedical and Cosmetic Applications | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. | 2017-12-14 | — | — | US | disclosed |
| EP-3226977-A2 | GLASS COMPOSITES FOR TISSUE AUGMENTATION, BIOMEDICAL AND COSMETIC APPLICATIONS | Augusta University Research Institute, Inc. (US) | 2017-10-11 | — | — | EP | disclosed |
| CN-102949387-B | For treating compositionss and the method for herpes simplex virus | 奥古斯塔大学研究所公司 | 2017-03-01 | — | — | CN | disclosed |
| US-9446017-B2 | Compositions and methods for treating herpes simplex virus | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. (US) | 2016-09-20 | — | — | US | disclosed |
| EP-1928415-A2 | TOPICAL DELIVERY WITH A CARRIER FLUID | Collegium Pharmaceutical, Inc. (US) | 2008-06-11 | — | — | EP | disclosed |
| EP-1922067-A1 | MODIFIED GREEN TEA POLYPHENOL FORMULATIONS | Medical College Of Georgia Research Institute (US) | 2008-05-21 | — | — | EP | disclosed |
| WO-2007021789-A1 | MODIFIED GREEN TEA POLYPHENOL FORMULATIONS | MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE (US) | 2007-02-22 | — | — | WO | disclosed |
| WO-2007022090-A2 | TOPICAL DELIVERY WITH A CARRIER FLUID | COLLEGIUM PHARMACEUTICAL, INC. (US) | 2007-02-22 | — | — | WO | disclosed |
| US-20070036731-A1 | Topical Delivery with a Carrier Fluid | COLLEGIUM PHARMACEUTICAL, INC. | 2007-02-15 | — | — | US | disclosed |
| WO-2006138056-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A MAHONIA AQUIFOLIUM EXTRACT FOR THE TREATMENT OF PSORIASIS | APOLLO PHARMACEUTICAL, INC. (US) | 2006-12-28 | — | — | WO | disclosed |
| US-20060286054-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF PSORIASIS | APOLLO PHARMACEUTICAL, INC. | 2006-12-21 | — | — | US | disclosed |
| WO-2005115336-A2 | SPRAYABLE FORMULATIONS FOR THE TREATMENT OF ACUTE INFLAMMATORY SKIN CONDITIONS | COLLEGIUM PHARMACEUTICAL, INC. (US) | 2005-12-08 | — | — | WO | disclosed |
| US-20050255048-A1 | Sprayable formulations for the treatment of acute inflammatory skin conditions | COLLEGIUM PHARMACEUTICAL, INC. | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060286054-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF PSORIASIS | VDR, CYP24A1, CYP2R1 | XIAP 3464/4885MAPT 814/4885KDM4E 601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.