Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27615467 | 0.76 | XIAP (0.48) | XIAPMEN1USP2ALDH1A1TP53 | |
| SCHEMBL2536906 | 0.71 | P2RX7 (0.35) | XIAPMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL223460 | 0.65 | ALDH1A1 (0.47) | MEN1USP2ALDH1A1LMNATP53 | |
| SCHEMBL871823 | 0.64 | XIAP (0.36) | XIAPMEN1USP2ALDH1A1LMNA | |
| SCHEMBL27797012 | 0.63 | KDM4E (0.44) | MEN1ALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL3320693 | 0.63 | KDM4E (0.44) | MEN1ALDH1A1LMNATP53CYP3A4 | |
| Water SCHEMBL9062657 | 0.63 | KDM4E (0.50) | MEN1ALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL5081850 | 0.63 | KDM4E (0.44) | MEN1ALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL5081810 | 0.63 | KDM4E (0.44) | MEN1ALDH1A1LMNATP53CYP3A4 | |
| SCHEMBL929847 | 0.63 | KDM4E (0.44) | MEN1ALDH1A1LMNATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928415-A2 | TOPICAL DELIVERY WITH A CARRIER FLUID | Collegium Pharmaceutical, Inc. (US) | 2008-06-11 | — | — | EP | claimed |
| WO-2007022090-A2 | TOPICAL DELIVERY WITH A CARRIER FLUID | COLLEGIUM PHARMACEUTICAL, INC. (US) | 2007-02-22 | — | — | WO | claimed |
| US-20070036731-A1 | Topical Delivery with a Carrier Fluid | COLLEGIUM PHARMACEUTICAL, INC. | 2007-02-15 | — | — | US | claimed |
| EP-3226977-B1 | GLASS COMPOSITES FOR TISSUE AUGMENTATION, BIOMEDICAL AND COSMETIC APPLICATIONS | UNIV RES INST INC AUGUSTA (US) | 2021-06-23 | — | — | EP | disclosed |
| US-20190117828-A1 | Glass Composites for Tissue Augmentation, Biomedical and Cosmetic Applications | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. | 2019-04-25 | — | — | US | disclosed |
| US-10201633-B2 | Glass composites for tissue augmentation, biomedical and cosmetic applications | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. (US) | 2019-02-12 | — | — | US | disclosed |
| US-9920058-B2 | Molecules with potent DHFR binding affinity and antibacterial activity | GEORGIA TECH RESEARCH CORPORATION (US) | 2018-03-20 | — | — | US | disclosed |
| US-20170354755-A1 | Glass Composites for Tissue Augmentation, Biomedical and Cosmetic Applications | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. | 2017-12-14 | — | — | US | disclosed |
| EP-3226977-A2 | GLASS COMPOSITES FOR TISSUE AUGMENTATION, BIOMEDICAL AND COSMETIC APPLICATIONS | Augusta University Research Institute, Inc. (US) | 2017-10-11 | — | — | EP | disclosed |
| CN-102949387-B | For treating compositionss and the method for herpes simplex virus | 奥古斯塔大学研究所公司 | 2017-03-01 | — | — | CN | disclosed |
| US-9446017-B2 | Compositions and methods for treating herpes simplex virus | AUGUSTA UNIVERSITY RESEARCH INSTITUTE, INC. (US) | 2016-09-20 | — | — | US | disclosed |
| EP-1928415-A2 | TOPICAL DELIVERY WITH A CARRIER FLUID | Collegium Pharmaceutical, Inc. (US) | 2008-06-11 | — | — | EP | disclosed |
| EP-1922067-A1 | MODIFIED GREEN TEA POLYPHENOL FORMULATIONS | Medical College Of Georgia Research Institute (US) | 2008-05-21 | — | — | EP | disclosed |
| WO-2007021789-A1 | MODIFIED GREEN TEA POLYPHENOL FORMULATIONS | MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE (US) | 2007-02-22 | — | — | WO | disclosed |
| WO-2007022090-A2 | TOPICAL DELIVERY WITH A CARRIER FLUID | COLLEGIUM PHARMACEUTICAL, INC. (US) | 2007-02-22 | — | — | WO | disclosed |
| US-20070036731-A1 | Topical Delivery with a Carrier Fluid | COLLEGIUM PHARMACEUTICAL, INC. | 2007-02-15 | — | — | US | disclosed |
| WO-2006138056-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A MAHONIA AQUIFOLIUM EXTRACT FOR THE TREATMENT OF PSORIASIS | APOLLO PHARMACEUTICAL, INC. (US) | 2006-12-28 | — | — | WO | disclosed |
| US-20060286054-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF PSORIASIS | APOLLO PHARMACEUTICAL, INC. | 2006-12-21 | — | — | US | disclosed |
| WO-2005115336-A2 | SPRAYABLE FORMULATIONS FOR THE TREATMENT OF ACUTE INFLAMMATORY SKIN CONDITIONS | COLLEGIUM PHARMACEUTICAL, INC. (US) | 2005-12-08 | — | — | WO | disclosed |
| US-20050255048-A1 | Sprayable formulations for the treatment of acute inflammatory skin conditions | COLLEGIUM PHARMACEUTICAL, INC. | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060286054-A1 | PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF PSORIASIS | VDR, CYP24A1, CYP2R1 | XIAP 3464/4885MEN1 3019/4885USP2 4703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.