SCHEMBL8718872

SCHEMBL8718872

Cl[SiH2]CCc1ccccc1CC[SiH2]Cl

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 10/20 0.37
IDO1 P14902 3/20 0.33
PNMT P11086 1/20 0.33
HTR2A P28223 1/20 0.33
HSPA5 P11021 1/20 0.31
AOC3 Q16853 2/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2684480 0.76 ALDH1A1 (0.48) TAAR1IDO1HTR2AAOC3SLC6A2
Chloromethane SCHEMBL29048090 0.72 ALDH1A1 (0.44) TAAR1HTR2AAOC3KCNH2
SCHEMBL8718870 0.71 GFER (0.36) TAAR1HTR2AAOC3SLC6A2
SCHEMBL2684572 0.67 HRH1 (0.55) TAAR1
SCHEMBL4574904 0.67 TAAR1 (0.40) TAAR1IDO1PNMTHTR2AHSPA5
SCHEMBL2272071 0.67 SIGMAR1 (0.48) IDO1HTR2ASLC6A3
SCHEMBL765987 0.61 TAAR1 (0.36) TAAR1IDO1PNMTHTR2AHSPA5
SCHEMBL2878727 0.61 SLC6A2 (0.43) TAAR1IDO1PNMTHTR2AHSPA5
SCHEMBL10534341 0.61 TSHR (0.41) TAAR1IDO1PNMTHTR2AHSPA5
SCHEMBL30997335 0.61 TAAR1 (0.36) TAAR1IDO1PNMTHTR2AHSPA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5726336-A REACTING A BENZENE COMPOUND WITH A VINYLCHLOROSILANE COMPOUND IN THE PRESENCE OF A LEWIS ACID CATALYST; INTERMEDIATES FOR SILICONE POLYMERS USEFUL AS EMULSIONS, GREASES, ADHESIVES, SEALANTS, COATINGS, IN AUTOMOTIVE AND ENGINEERING FIELDS KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 1998-03-10 US disclosed