Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430263 | 0.76 | SIGMAR1 (0.50) | CYP2D6TSHRSIGMAR1CYP1A2L3MBTL1 | |
| SCHEMBL8713645 | 0.75 | SIGMAR1 (0.44) | CYP2D6TSHRSIGMAR1CYP1A2MAOB | |
| SCHEMBL8714026 | 0.73 | MAOB (0.49) | MEN1KMT2ASIGMAR1MAOB | |
| SCHEMBL8713719 | 0.72 | MAPT (0.42) | CYP2C19CYP3A4TSHRMEN1LMNA | |
| SCHEMBL8714022 | 0.71 | SIGMAR1 (0.43) | USP2CYP2D6CYP2C19CYP3A4TSHR | |
| SCHEMBL8718156 | 0.70 | SIGMAR1 (0.42) | KMT2ASIGMAR1L3MBTL1 | |
| SCHEMBL8716243 | 0.70 | ACHE (0.46) | CYP2D6CYP3A4TSHRALOX15KMT2A | |
| SCHEMBL8713177 | 0.70 | SIGMAR1 (0.40) | CYP2D6TSHRSIGMAR1CYP1A2MAOB | |
| SCHEMBL8714206 | 0.70 | SIGMAR1 (0.44) | CYP2D6TSHRSIGMAR1CYP1A2NPY5R | |
| SCHEMBL8718245 | 0.69 | PNMT (0.42) | TSHRSIGMAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811293-A | CULTURE PRODUCT AS CHEMICAL INTERMEDIATE FOR ANTI-OBESITY AGENT | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-22 | — | — | US | disclosed |