Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | DRD3 | P35462 | 3/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 6/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30306331 | 1.00 | DRD2 (0.52) | DRD2DRD3HTR1ASLC6A2SLC6A4 | |
| SCHEMBL14355885 | 0.86 | HTR1A (0.68) | DRD2DRD3HTR1ASLC6A2SLC6A4 | |
| SCHEMBL30306319 | 0.86 | HSP90AB1 (0.41) | DRD2DRD3 | |
| SCHEMBL29135242 | 0.86 | HSP90AB1 (0.41) | DRD2DRD3 | |
| SCHEMBL30306325 | 0.82 | HTR1A (0.52) | DRD2DRD3HTR1ASLC6A2SLC6A4 | |
| SCHEMBL9332845 | 0.80 | DRD2 (0.67) | DRD2DRD3HTR1ADRD4ALDH1A1 | |
| SCHEMBL8720341 | 0.80 | ADRA1D (0.65) | DRD2DRD3HTR1AKDM4EALDH1A1 | |
| SCHEMBL30306326 | 0.80 | HRH4 (0.49) | KDM4EALDH1A1TDP1 | |
| SCHEMBL24712696 | 0.80 | DRD2 (0.56) | DRD2DRD3HTR1AKDM4EALDH1A1 | |
| SCHEMBL8894896 | 0.79 | ALDH1A1 (0.57) | DRD2DRD3HTR1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117957232-A | Azaindazole macrocyclic compounds and uses thereof | 北京伯汇生物技术有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-115838373-A | Azaindazole macrocycles and uses thereof | 北京伯汇生物技术有限公司 | 2023-03-24 | — | — | CN | disclosed |