Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 7/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | PDCD1LG2 | Q9BQ51 | 3/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8719819 | 0.84 | OPRK1 (0.41) | OPRK1OPRM1MAPTKDM4EMEN1 | |
| SCHEMBL6425483 | 0.79 | KCNA3 (0.44) | OPRK1OPRM1KDM4EOPRD1LTA4H | |
| SCHEMBL8720345 | 0.77 | OPRK1 (0.42) | OPRK1MEN1KMT2A | |
| SCHEMBL8720379 | 0.75 | ALDH1A1 (0.39) | OPRK1KDM4EOPRD1 | |
| SCHEMBL8716993 | 0.72 | ALDH1A1 (0.40) | OPRK1KDM4E | |
| SCHEMBL8717430 | 0.72 | ALDH1A1 (0.37) | OPRK1KDM4EPDCD1LG2CD274 | |
| SCHEMBL8717616 | 0.72 | ALDH1A1 (0.37) | OPRK1OPRM1KDM4EOPRD1LTA4H | |
| SCHEMBL8719953 | 0.70 | ALDH1A1 (0.42) | MAPTMEN1KMT2ALTA4H | |
| SCHEMBL8809772 | 0.70 | OPRK1 (0.41) | OPRK1OPRM1KDM4EOPRD1MEN1 | |
| SCHEMBL16487251 | 0.68 | CA1 (0.44) | MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0569802-B1 | Arylacetamides | MERCK PATENT GMBH (DE) | 1998-07-15 | — | — | EP | disclosed |
| EP-0569802-A1 | Arylacetamides | MERCK PATENT GmbH (DE) | 1993-11-18 | — | — | EP | disclosed |