Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | MPI | P34949 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 3/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PELI1 | Q96FA3 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | BCR | P11274 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1535921 | 0.80 | BACE1 (0.68) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL456551 | 0.80 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL15261306 | 0.80 | ALDH1A1 (0.59) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL27928636 | 0.78 | ALDH1A1 (0.45) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| Potassium SCHEMBL29843830 | 0.78 | ALDH1A1 (0.45) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL11328974 | 0.78 | ALDH1A1 (0.57) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL2861901 | 0.77 | ALOX5 (0.59) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL29674576 | 0.77 | ALOX5 (0.59) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL7900444 | 0.76 | METAP2 (0.46) | ALDH1A1BACE1ALOX5ESR2CA12 | |
| SCHEMBL28926510 | 0.76 | ESR2 (0.57) | ALDH1A1HPGDKDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0662004-B1 | USE OF PERSISTENT FREE-RADICALS IN MAGNETIC RESONANCE IMAGING | NYCOMED INNOVATION AB (SE) | 1998-03-18 | — | — | EP | disclosed |
| US-5700448-A | Use of persistent free-radicals in magnetic resonance imaging | NYCOMED IMAGING AS (NO) | 1997-12-23 | — | — | US | disclosed |
| US-5435991-A | Use of persistent heterocyclic free-radicals in magnetic resonance imaging | NYCOMED INNOVATION AB (SE) | 1995-07-25 | — | — | US | disclosed |
| EP-0662004-A1 | USE OF PERSISTENT FREE-RADICALS IN MAGNETIC RESONANCE IMAGING | Nycomed Innovation AB (SE) | 1995-07-12 | — | — | EP | disclosed |
| WO-1993002710-A2 | USE OF PERSISTENT FREE RADICALS IN MAGNETIC RESONANCE IMAGING | NYCOMED INNOVATION AB (SE) | 1993-02-18 | — | — | WO | disclosed |
| WO-1993002711-A1 | USE OF PERSISTENT FREE-RADICALS IN MAGNETIC RESONANCE IMAGING | NYCOMED INNOVATION AB (SE) | 1993-02-18 | — | — | WO | disclosed |