Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 18/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 18/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 17/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 9/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8722759 | 0.85 | ALDH1A1 (0.55) | ADORA3L3MBTL1 | |
| SCHEMBL8724476 | 0.83 | JUN (0.44) | — | |
| SCHEMBL8721300 | 0.82 | RAB9A (0.52) | — | |
| SCHEMBL8722769 | 0.81 | JUN (0.57) | — | |
| SCHEMBL8726399 | 0.80 | RAB9A (0.42) | — | |
| SCHEMBL8725171 | 0.80 | NFKB1 (0.52) | — | |
| SCHEMBL8724454 | 0.78 | HSP90AA1 (0.55) | — | |
| SCHEMBL8721318 | 0.77 | RAB9A (0.38) | ADORA3ADORA2AADORA1 | |
| SCHEMBL8721324 | 0.77 | KDM4E (0.56) | L3MBTL1 | |
| SCHEMBL8721404 | 0.77 | NFKB1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998038171-A1 | PYRIMIDINE CARBOXYLATES AND RELATED COMPOUNDS AND METHODS FOR TREATING INFLAMMATORY CONDITIONS | SIGNAL PHARMACEUTICALS, INC. (US) | 1998-09-03 | — | — | WO | disclosed |
| WO-1997009325-A1 | PYRIMIDINE CARBOXYLATES AND RELATED COMPOUNDS AND METHODS FOR TREATING INFLAMMATORY CONDITIONS | SIGNAL PHARMACEUTICALS, INC. (US) | 1997-03-13 | — | — | WO | disclosed |