Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 2/20 | 0.44 |
| ▸ | JAK3 | P52333 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8724476 | 0.86 | JUN (0.44) | ALDH1A1SMN1; SMN2MAPTLMNAMAPK1 | |
| SCHEMBL8721300 | 0.85 | RAB9A (0.52) | ALDH1A1SMN1; SMN2MAPTMAPK1RAB9A | |
| SCHEMBL8722135 | 0.85 | ADORA3 (0.48) | L3MBTL1ADORA3 | |
| SCHEMBL8722769 | 0.85 | JUN (0.57) | ALDH1A1SMN1; SMN2MAPTLMNAMAPK1 | |
| SCHEMBL8726399 | 0.83 | RAB9A (0.42) | ALDH1A1SMN1; SMN2MAPTMAPK1RAB9A | |
| SCHEMBL8725171 | 0.83 | NFKB1 (0.52) | ALDH1A1SMN1; SMN2MAPTRAB9ANPSR1 | |
| SCHEMBL8721318 | 0.82 | RAB9A (0.38) | ALDH1A1SMN1; SMN2MAPTLMNAMAPK1 | |
| SCHEMBL8721338 | 0.82 | MAPK1 (0.41) | ALDH1A1MAPK1KDM4EKMT2ATSHR | |
| SCHEMBL8724454 | 0.81 | HSP90AA1 (0.55) | ALDH1A1SMN1; SMN2MAPTLMNAMAPK1 | |
| SCHEMBL8721324 | 0.80 | KDM4E (0.56) | MAPTRAB9ANPSR1NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998038171-A1 | PYRIMIDINE CARBOXYLATES AND RELATED COMPOUNDS AND METHODS FOR TREATING INFLAMMATORY CONDITIONS | SIGNAL PHARMACEUTICALS, INC. (US) | 1998-09-03 | — | — | WO | disclosed |