Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 13/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383413 | 0.84 | NNMT (0.70) | NNMTHCAR3KDM4E | |
| SCHEMBL158601 | 0.84 | HCAR3 (0.67) | HCAR3HCAR2 | |
| SCHEMBL29505896 | 0.84 | HCAR3 (0.67) | HCAR3HCAR2 | |
| SCHEMBL11005841 | 0.82 | NNMT (0.53) | NNMTHCAR3HCAR2KDM4EGAA | |
| Hydrochloric Acid SCHEMBL5789616 | 0.82 | HCAR3 (0.65) | HCAR3HCAR2 | |
| Ammonia Solution, Strong SCHEMBL28249483 | 0.82 | HCAR3 (0.65) | HCAR3HCAR2 | |
| SCHEMBL217496 | 0.82 | NNMT (0.49) | NNMTHCAR3HCAR2KDM4EMAPT | |
| SCHEMBL8815728 | 0.82 | NNMT (0.49) | NNMTHCAR3HCAR2 | |
| Hydrazine SCHEMBL628678 | 0.82 | NNMT (0.68) | NNMTHCAR3KDM4E | |
| SCHEMBL2487358 | 0.79 | NNMT (0.54) | NNMTHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753520-A | BIOCHEMICAL CONJUGATED WITH A HYDRAZINE OR A HYDRAZONE COMPOUND AS DRUG DELIVERY; HIGH BIOLOGICAL SPECIFICITY; MEDICINE FOR IMAGING, THERAPY, RADIOACTIVE TAGGING | JOHNSON MATTHEY INC. (US) | 1998-05-19 | — | — | US | disclosed |