Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.35 |
| ▸ | GPR68 | Q15743 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5475553 | 0.76 | CASP3 (0.52) | ALDH1A1IDO1HSD17B10SENP7SMN1; SMN2 | |
| SCHEMBL30584864 | 0.76 | NPC1 (0.44) | ALDH1A1L3MBTL1SENP7SMN1; SMN2NPC1 | |
| SCHEMBL10396259 | 0.76 | NPC1 (0.44) | ALDH1A1L3MBTL1SENP7SMN1; SMN2NPC1 | |
| SCHEMBL4337968 | 0.76 | NPC1 (0.45) | ALDH1A1L3MBTL1HSD17B10SENP7SMN1; SMN2 | |
| SCHEMBL1949784 | 0.76 | RAB9A (0.43) | ALDH1A1L3MBTL1IDO1HSD17B10SMN1; SMN2 | |
| SCHEMBL6422966 | 0.73 | KDM4E (0.47) | ALDH1A1L3MBTL1BCHEACHEHSD17B10 | |
| SCHEMBL29371089 | 0.73 | NPC1 (0.51) | ALDH1A1HSD17B10KDM4ENPC1RAB9A | |
| SCHEMBL31155670 | 0.72 | PLAU (0.37) | ALDH1A1L3MBTL1ACHEHSD17B10SMN1; SMN2 | |
| SCHEMBL15332604 | 0.72 | LMNA (0.41) | ALDH1A1SMN1; SMN2GAAHPGDCASP6 | |
| SCHEMBL22455491 | 0.72 | CASP6 (0.33) | CASP6PPARAADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200299282-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | ANTIDOTE IP HOLDINGS LLC (US) | 2020-09-24 | — | — | US | disclosed |
| US-20200299282-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | ANTIDOTE IP HOLDINGS LLC (US) | 2020-09-24 | — | — | US | disclosed |
| US-5854261-A | Prokinetic compounds | JANSSEN PHARMACEUTICA N.V. (BE) | 1998-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200299282-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | VHL, TP53, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | ALDH1A1 118/4885L3MBTL1 3400/4885BCHE 1460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.