Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30584864 | 1.00 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2TP53HPGD | |
| SCHEMBL30584710 | 0.81 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2TP53HPGD | |
| SCHEMBL493335 | 0.78 | KMO (0.42) | NOTUMGRM5KMOCYP2A6CYP1A2 | |
| SCHEMBL493530 | 0.77 | GRM5 (0.43) | NPC1RAB9ASMN1; SMN2TP53HPGD | |
| SCHEMBL1949784 | 0.76 | RAB9A (0.43) | NPC1RAB9ASMN1; SMN2TP53HPGD | |
| SCHEMBL17984215 | 0.76 | GPR55 (0.47) | NPC1RAB9ASMN1; SMN2TP53HPGD | |
| SCHEMBL5475553 | 0.76 | CASP3 (0.52) | NPC1RAB9ASMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL4337968 | 0.76 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2TP53HPGD | |
| SCHEMBL8722639 | 0.76 | ALDH1A1 (0.46) | NPC1RAB9ASMN1; SMN2HPGDCYP3A4 | |
| SCHEMBL16787390 | 0.74 | KMO (0.44) | NPC1RAB9ATP53HPGDKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4919703-A | Method of stimulating the growth of plants employing substituted oxadiazoles | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1990-04-24 | — | — | US | disclosed |