Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 3/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | MMP12 | P39900 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | MMP14 | P50281 | 2/20 | 0.33 |
| ▸ | MMP16 | P51512 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603532 | 0.82 | ADAMTS4 (0.44) | RENMMP1MMP2MMP9MMP13 | |
| SCHEMBL8722719 | 0.78 | ALDH1A1 (0.40) | RENALDH1A1 | |
| SCHEMBL8603277 | 0.76 | ALDH1A1 (0.55) | ALDH1A1MMP1MMP2MMP9MMP13 | |
| SCHEMBL9152342 | 0.73 | HTR6 (0.42) | L3MBTL1KCNA5ALDH1A1HTR6MMP1 | |
| SCHEMBL8653117 | 0.73 | HTR6 (0.58) | ALDH1A1HTR6MMP1MMP2MMP9 | |
| SCHEMBL8603733 | 0.73 | GAA (0.34) | RENL3MBTL1ALDH1A1MMP1MMP9 | |
| SCHEMBL7365219 | 0.72 | HTR6 (0.41) | L3MBTL1KCNA5ALDH1A1HTR6MMP1 | |
| SCHEMBL3652033 | 0.68 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1 | |
| SCHEMBL7558532 | 0.68 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1 | |
| SCHEMBL1900804 | 0.68 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792869-A | REACTING PIPERAZINE DERIVATIVE WITH SULFONAMIDE DERIVATIVE OF OPTICALLY ACTIVE AMINO ACID, PRECIPITATING LESS SOLUBLE SALT, SEPARATING, DECOMPOSING TO DESIRED DIASTEREOMER | YAMAKAWA CHEMICAL INDUSTRY CO., LTD (JP) | 1998-08-11 | — | — | US | disclosed |