Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.34 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | CLK2 | P49760 | 1/20 | 0.33 |
| ▸ | CLK3 | P49761 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845622 | 0.91 | ITGB1 (0.42) | ITGB1ITGA4PAX8HRH3TBXAS1 | |
| SCHEMBL872553 | 0.90 | ITGB1 (0.39) | ITGB1ITGA4PDE3BPARP1POLB | |
| SCHEMBL845351 | 0.88 | ITGB1 (0.41) | ITGB1ITGA4PAX8HRH3TBXAS1 | |
| SCHEMBL10119279 | 0.84 | EPHX2 (0.37) | ITGB1ITGA4PARP1HTR1ADRD2 | |
| SCHEMBL845334 | 0.84 | ITGB1 (0.39) | ITGB1ITGA4PAX8HRH3TBXAS1 | |
| SCHEMBL845099 | 0.80 | ITGB1 (0.44) | ITGB1ITGA4PDE3BPOLB | |
| SCHEMBL13272184 | 0.80 | PDE3B (0.34) | ITGB1ITGA4PAX8PDE3BNAMPT | |
| SCHEMBL872031 | 0.78 | PTPN1 (0.34) | POLBNAMPT | |
| SCHEMBL845098 | 0.77 | ITGB1 (0.43) | ITGB1ITGA4PDE3BPOLB | |
| SCHEMBL10119337 | 0.75 | ADRB1 (0.36) | ITGB1ITGA4PAX8HRH3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |