Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL845622 | 0.96 | ITGB1 (0.42) | ITGB1ITGA4PAX8HRH3TBXAS1 | |
| SCHEMBL845334 | 0.89 | ITGB1 (0.39) | ITGB1ITGA4PAX8HRH3TBXAS1 | |
| SCHEMBL845098 | 0.89 | ITGB1 (0.43) | ITGB1ITGA4ALDH1A1HTTKMT2A | |
| SCHEMBL872288 | 0.88 | ITGB1 (0.37) | ITGB1ITGA4PAX8HRH3TBXAS1 | |
| SCHEMBL873383 | 0.84 | CHRNA7 (0.36) | ALDH1A1HTTCYP17A1CYP21A2CYP11B1 | |
| SCHEMBL845099 | 0.84 | ITGB1 (0.44) | ITGB1ITGA4ALDH1A1HTTKMT2A | |
| SCHEMBL845086 | 0.82 | EPHX2 (0.40) | ITGB1ITGA4ALDH1A1KMT2AMAPT | |
| SCHEMBL845097 | 0.82 | NAMPT (0.39) | ITGB1ITGA4ALDH1A1HTTKMT2A | |
| SCHEMBL845401 | 0.81 | ALDH1A1 (0.45) | ITGB1ITGA4PAX8HRH3ALDH1A1 | |
| SCHEMBL10119337 | 0.79 | ADRB1 (0.36) | ITGB1ITGA4PAX8HRH3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |
| US-8143288-B2 | Inhibitors of HCV replication | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-03-27 | — | — | US | disclosed |