Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL776296 | 0.79 | CYP2C19 (0.36) | CYP2C19LMNATDP1 | |
| Biphenyl SCHEMBL4602174 | 0.74 | TP53 (0.48) | LMNAAKT1 | |
| Benzene SCHEMBL17022335 | 0.73 | — | — | |
| SCHEMBL9068192 | 0.69 | ALDH1A1 (0.42) | CYP2C19LMNAHPGDCYP2D6 | |
| SCHEMBL176352 | 0.69 | — | — | |
| SCHEMBL776368 | 0.67 | CYP2C19 (0.36) | CYP2C19LMNAHPGDCYP2D6SRC | |
| SCHEMBL9067882 | 0.66 | CYP2C19 (0.36) | CYP2C19LMNAEPHX1 | |
| SCHEMBL8359285 | 0.65 | CYP2C19 (0.48) | CYP2C19LMNAHPGDCYP2D6SRC | |
| SCHEMBL1004825 | 0.65 | CYP2C19 (0.33) | CYP2C19LMNA | |
| SCHEMBL2046183 | 0.65 | LMNA (0.37) | CYP2C19LMNAHPGDMAPK1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708064-A | CONTAINING THERMOSETTING RESIN | PPG INDUSTRIES, INC. (US) | 1998-01-13 | — | — | US | disclosed |