Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP12 | P39900 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | ESRRA | P11474 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8726177 | 0.88 | ALDH1A1 (0.37) | UTS2REGFRERBB2ESRRAALDH1A1 | |
| SCHEMBL8722158 | 0.87 | CA2 (0.41) | CA1CA12CA9UTS2RBCL2L1 | |
| SCHEMBL8724202 | 0.81 | EGFR (0.43) | CA1CA12CA9UTS2REGFR | |
| SCHEMBL8722146 | 0.81 | CA1 (0.43) | CA1CA12CA9UTS2RCA2 | |
| SCHEMBL7715738 | 0.81 | CA1 (0.44) | CA1CA12CA9UTS2REGFR | |
| SCHEMBL7715732 | 0.80 | EGFR (0.53) | CA1CA12CA9UTS2REGFR | |
| SCHEMBL8726211 | 0.79 | NPSR1 (0.37) | CA1CA12CA9UTS2RMMP2 | |
| SCHEMBL8726250 | 0.75 | ALDH1A1 (0.35) | CA1CA12CA9ALDH1A1MCHR1 | |
| SCHEMBL8722080 | 0.74 | MMP2 (0.55) | CA1CA12CA9UTS2RMMP2 | |
| SCHEMBL8726236 | 0.73 | TAS1R3 (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998035982-A1 | COMPOUNDS FOR USE IN ADEPT | ZENECA LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |