Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 13/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 10/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | RNF4 | P78317 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8722093 | 0.75 | MAPT (0.47) | MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7711928 | 0.75 | MCL1 (0.43) | LPAR1LPAR5 | |
| SCHEMBL7715738 | 0.71 | CA1 (0.44) | MEN1KMT2A | |
| SCHEMBL8728069 | 0.70 | SMN1; SMN2 (0.38) | PTGES | |
| SCHEMBL8722150 | 0.69 | CA2 (0.42) | — | |
| SCHEMBL8727972 | 0.69 | ALDH1A1 (0.43) | NPC1RAB9A | |
| SCHEMBL7711926 | 0.69 | ESRRA (0.36) | KMT2ARAB9A | |
| SCHEMBL8726548 | 0.69 | ALDH1A1 (0.43) | NPC1RAB9A | |
| SCHEMBL7717406 | 0.68 | LPAR1 (0.33) | LPAR1LPAR5 | |
| SCHEMBL1395690 | 0.67 | ALDH1A1 (0.48) | MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998035982-A1 | COMPOUNDS FOR USE IN ADEPT | ZENECA LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |