Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6652780 | 0.92 | ALDH1A1 (0.34) | ALDH1A1MAPTHPGDKDM4EGAA | |
| SCHEMBL8978567 | 0.88 | MAPT (0.45) | ALDH1A1MAPTHPGDKDM4EGAA | |
| SCHEMBL8978547 | 0.85 | RAB9A (0.39) | ALDH1A1RAB9ATP53TDP1L3MBTL1 | |
| SCHEMBL5646759 | 0.84 | RAB9A (0.38) | ALDH1A1HPGDKDM4ERAB9ATP53 | |
| SCHEMBL6653783 | 0.80 | ALDH1A1 (0.40) | ALDH1A1MAPTHPGDKDM4EGAA | |
| SCHEMBL9280386 | 0.80 | ATM (0.38) | ALDH1A1MAPTHPGDKDM4ERAB9A | |
| SCHEMBL5646592 | 0.79 | RAB9A (0.34) | ALDH1A1KDM4EGAARAB9ATDP1 | |
| SCHEMBL6169861 | 0.75 | ATM (0.41) | ALDH1A1MAPTHPGDKDM4ERAB9A | |
| SCHEMBL13988301 | 0.75 | L3MBTL1 (0.37) | ALDH1A1MAPTRAB9ATP53TDP1 | |
| SCHEMBL1333703 | 0.75 | ATM (0.39) | ALDH1A1MAPTRAB9ATP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5573712-A | PHOTOCHROMIC ARTICLE COMPRISING ORGANIC HOST AND THE PHOTOCHROMIC NAPHTHOPYRAN | TRANSITIONS OPTICAL, INC. (US) | 1996-11-12 | — | — | US | claimed |
| WO-1995016215-A1 | NOVEL SUBSTITUTED NAPHTHOPYRANS | PPG INDUSTRIES, INC. (US) | 1995-06-15 | — | — | WO | claimed |
| US-5573712-A | PHOTOCHROMIC ARTICLE COMPRISING ORGANIC HOST AND THE PHOTOCHROMIC NAPHTHOPYRAN | TRANSITIONS OPTICAL, INC. (US) | 1996-11-12 | — | — | US | disclosed |
| US-5458814-A | Ophthalmic lenses | TRANSITIONS OPTICAL, INC. (US) | 1995-10-17 | — | — | US | disclosed |