Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.36 |
| ▸ | LTA4H | P09960 | 3/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | YAP1 | P46937 | 2/20 | 0.33 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3700726 | 0.81 | LDHA (0.50) | PPARAPPARGLDHA | |
| SCHEMBL8732292 | 0.76 | ACACB (0.48) | ITGB3ITGA2BHDAC8ACACB | |
| SCHEMBL23792335 | 0.74 | LOXL2 (0.53) | — | |
| SCHEMBL8732650 | 0.72 | SLC6A4 (0.54) | — | |
| SCHEMBL1822640 | 0.71 | P2RX7 (0.49) | PPARG | |
| SCHEMBL8732412 | 0.71 | CA2 (0.47) | ACACBPTPN1 | |
| SCHEMBL3697349 | 0.71 | PPARG (0.44) | PPARG | |
| Thiophene SCHEMBL27291067 | 0.70 | ITGA4 (0.43) | — | |
| SCHEMBL8758138 | 0.68 | MAOB (0.50) | — | |
| SCHEMBL27514471 | 0.68 | LTA4H (0.53) | LTA4HYAP1PPARABCL2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5726165-A | HYPOGLYCEMIC AGENTS; DIETETICS; GASTROINTESTINAL DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 1998-03-10 | — | — | US | disclosed |