SCHEMBL873369

SCHEMBL873369

CCCCC(=O)OCC(C)(C)CCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.47
PAM P19021 2/20 0.43
CYP1A2 P05177 1/20 0.42
TSHR P16473 2/20 0.41
MAPT P10636 1/20 0.41
LMNA P02545 3/20 0.40
HSD17B10 Q99714 1/20 0.40
DNM1 Q05193 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CYP3A4 P08684 1/20 0.40
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
KDM4E B2RXH2 1/20 0.39
DUSP3 P51452 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
P2RY10 O00398 1/20 0.38
GPR34 Q9UPC5 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6406466 0.90 DGKA (0.52) DGKAPAMCYP1A2TSHRMAPT
SCHEMBL6669210 0.85 DGKA (0.58) DGKAPAMTSHRMAPTLMNA
SCHEMBL18871392 0.84 P2RY10 (0.56) DGKACYP1A2TSHRMAPTLMNA
SCHEMBL855142 0.84 DGKA (0.61) DGKAPAMTSHRMAPTLMNA
SCHEMBL17812465 0.82 DGKA (0.64) DGKAPAMTSHRMAPTLMNA
SCHEMBL480307 0.82 DGKA (0.64) DGKAPAMTSHRMAPTLMNA
SCHEMBL1881320 0.82 DGKA (0.64) DGKAPAMTSHRMAPTLMNA
SCHEMBL11979358 0.82 DGKA (0.64) DGKAPAMTSHRMAPTLMNA
SCHEMBL11979360 0.82 DGKA (0.64) DGKAPAMTSHRMAPTLMNA
SCHEMBL33575 0.82 DGKA (0.64) DGKAPAMTSHRMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10015984-B2 Disintegrable capsule, manufacturing method for same, and smoking device containing said disintegrable capsule SUNSHO PHARMACEUTICAL CO., LTD. (JP) 2018-07-10 US disclosed
US-20170196848-A1 Prodrugs of NH-Acidic Compounds: Ester, Carbonate, Carbamate and Phosphonate Derivatives ALKERMES PHARMA IRELAND LTD (IE) 2017-07-13 US disclosed
US-9358191-B2 Deodorant composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2016-06-07 US disclosed
EP-2997837-A1 DISINTEGRABLE CAPSULE, MANUFACTURING METHOD FOR SAME, AND SMOKING EQUIPMENT CONTAINING SAID DISINTEGRABLE CAPSULE Sunsho Pharmaceutical Co., Ltd. (JP) 2016-03-23 EP disclosed
US-20160021927-A1 DISINTEGRABLE CAPSULE, MANUFACTURING METHOD FOR SAME, AND SMOKING EQUIPMENT CONTAINING SAID DISINTEGRABLE CAPSULE SUNSHO PHARMACEUTICAL CO., LTD. (JP) 2016-01-28 US disclosed
US-20150266847-A1 MACROCYCLIC TRIENE LACTONES HAVING UNCONJUGATED TRIENE STRUCTURE, ITS PRODUCTION METHOD AND ITS SYNTHETIC INTERMEDIATE TAKASAGO INTERNATIONAL CORPORATION (JP) 2015-09-24 US disclosed
US-9085545-B2 Macrocyclic triene lactones having unconjugated triene structure, its production method and its synthetic intermediate TAKASAGO INTERNATIONAL CORPORATION (JP) 2015-07-21 US disclosed
US-8961946-B2 Hair processing agent and method for permanent waving hair SHOWA DENKO K.K. (JP) 2015-02-24 US disclosed
US-20140271522-A1 DEODORANT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-09-18 US disclosed
US-8778320-B2 Deodorant composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2014-07-15 US disclosed
EP-2618856-A1 DEODORANT COMPOSITION FOR SULFIDES Takasago International Corporation (JP) 2013-07-31 EP disclosed
US-20130136713-A1 DEODORANT COMPOSITION FOR SULFIDES TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-05-30 US disclosed
WO-2012115285-A1 MACROCYCLIC TRIENE LACTONES HAVING UNCONJUGATED TRIENE STRUCTURE, ITS PRODUCTION METHOD AND ITS SYNTHETIC INTERMEDIATE TAKASAGO INTERNATIONAL CORPORATION (JP) 2012-08-30 WO disclosed
WO-2012039516-A1 DEODORANT COMPOSITION FOR SULFIDES TAKASAGO INTERNATIONAL CORPORATION (JP) 2012-03-29 WO disclosed
US-20090087401-A1 DEODORANT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-04-02 US disclosed
US-20080085251-A1 even at a neutral to weakly acidic pH; a lactone or lactam having a mercapto group; with thioglycolic acid, thiolactic acid, cysteine, acetylcysteine, cysteamine, acylcysteamine; RESONAC CORPORATION (JP) 2008-04-10 US disclosed
EP-1827370-A1 HAIR PROCESSING AGENT AND METHOD FOR PERMANENT WAVING HAIR Showa Denko K.K. (JP) 2007-09-05 EP disclosed
US-20060165622-A1 Deodorant composition TAKASAGO INTERNATIONAL CORPORATION (JP) 2006-07-27 US disclosed
WO-2006068276-A1 HAIR PROCESSING AGENT AND METHOD FOR PERMANENT WAVING HAIR SHOWA DENKO K.K. (JP) 2006-06-29 WO disclosed
EP-1561476-A1 DEODORANT COMPOSITION Takasago International Corporation (JP) 2005-08-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170196848-A1 Prodrugs of NH-Acidic Compounds: Ester, Carbonate, Carbamate and Phosphonate Derivatives PHPT1, SI, CA6 DGKA 3999/4885PAM 111/4885CYP1A2 1838/4885
US-20150266847-A1 MACROCYCLIC TRIENE LACTONES HAVING UNCONJUGATED TRIENE STRUCTURE, ITS PRODUCTION METHOD AND ITS SYNTHETIC INTERMEDIATE TAS2R13, TAS2R40, TAS2R14 DGKA 224/4885PAM 208/4885CYP1A2 829/4885
US-20080085251-A1 even at a neutral to weakly acidic pH; a lactone or lactam having a mercapto group; with thioglycolic acid, thiolactic acid, cysteine, acetylcysteine, cysteamine, acylcysteamine; TST, CYSLTR1, CYSLTR2 DGKA 3278/4885PAM 131/4885CYP1A2 373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.