Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29663898 | 0.85 | MAPK1 (0.68) | ALDH1A1SMN1; SMN2MAPK1CA1CA2 | |
| SCHEMBL51046 | 0.85 | MAPK1 (0.68) | ALDH1A1SMN1; SMN2MAPK1CA1CA2 | |
| SCHEMBL8703196 | 0.84 | MAPK1 (0.58) | ALDH1A1SMN1; SMN2HPGDGLO1MAPK1 | |
| SCHEMBL28490306 | 0.78 | GAA (0.51) | ALDH1A1SMN1; SMN2HPGDMAPK1CA1 | |
| SCHEMBL28476864 | 0.75 | MAPK1 (0.54) | ALDH1A1SMN1; SMN2HPGDMAPK1CA1 | |
| SCHEMBL8590457 | 0.75 | MAPK1 (0.48) | ALDH1A1SMN1; SMN2HPGDGLO1MAPK1 | |
| SCHEMBL14875890 | 0.74 | KDM4E (0.49) | ALDH1A1SMN1; SMN2GLO1MAPK1CA1 | |
| SCHEMBL4438 | 0.73 | CA2 (0.58) | ALDH1A1SMN1; SMN2HPGDCA1CA2 | |
| SCHEMBL6894312 | 0.72 | GLO1 (0.61) | ALDH1A1SMN1; SMN2HPGDGLO1MAPK1 | |
| SCHEMBL3706122 | 0.71 | SMN1; SMN2 (1.00) | ALDH1A1SMN1; SMN2HPGDGLO1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0865439-A4 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS INC (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0865439-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1998-09-23 | — | — | EP | disclosed |
| WO-1996040672-A1 | COMBINATORIAL LIBRARIES HAVING AMINODIOL MONOMER SUBUNITS | ISIS PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |