Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.54 |
| ▸ | METAP2 | P50579 | 2/20 | 0.54 |
| ▸ | METAP1 | P53582 | 2/20 | 0.54 |
| ▸ | G6PD | P11413 | 1/20 | 0.54 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.54 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29663898 | 0.92 | MAPK1 (0.68) | MAPK1CA1CA2CA9MAPT | |
| SCHEMBL51046 | 0.92 | MAPK1 (0.68) | MAPK1CA1CA2CA9MAPT | |
| SCHEMBL8590457 | 0.89 | MAPK1 (0.48) | MAPK1CA1CA2CA9MAPT | |
| SCHEMBL8734368 | 0.84 | ALDH1A1 (0.55) | MAPK1CA1CA2CA9MAPT | |
| SCHEMBL6894312 | 0.84 | GLO1 (0.61) | MAPK1CA1CA2CA9MAPT | |
| SCHEMBL28490306 | 0.84 | GAA (0.51) | MAPK1CA1CA2CA9MAPT | |
| SCHEMBL13241507 | 0.83 | MAPK1 (0.62) | MAPK1CA1CA2CA9MAPT | |
| SCHEMBL13241501 | 0.82 | MAPK1 (0.60) | MAPK1CA1CA2CA9MAPT | |
| SCHEMBL28476864 | 0.81 | MAPK1 (0.54) | MAPK1CA1CA2CA9MAPT | |
| SCHEMBL8675683 | 0.80 | SLC40A1 (0.43) | MAPK1CA1CA2CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008813-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED PYRROLIDINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |