SCHEMBL8734771

SCHEMBL8734771

Cc1cccc(Cl)c1S(=O)(=O)OC[PH](=O)O

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SLC40A1 Q9NP59 1/20 0.35
KMT2A Q03164 2/20 0.33
NR3C1 P04150 1/20 0.33
CCR1 P32246 3/20 0.33
ESR1 P03372 2/20 0.33
ATM Q13315 1/20 0.32
LMNA P02545 3/20 0.32
ALDH1A1 P00352 2/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
AKR1C3 P42330 1/20 0.31
PKM P14618 1/20 0.31
GAA P10253 1/20 0.31
POLB P06746 1/20 0.31
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8731854 0.89 KMT2A (0.34) KMT2AATMLMNAALDH1A1PKM
SCHEMBL8764019 0.87 SLC40A1 (0.36) SLC40A1KMT2ANR3C1CCR1ESR1
SCHEMBL8854564 0.83 SLC40A1 (0.34) SLC40A1KMT2ANR3C1CCR1ESR1
SCHEMBL8735700 0.82 CXCL8 (0.33) LMNATSHRELANE
SCHEMBL27288328 0.80 PNMT (0.42)
SCHEMBL8734852 0.80 LMNA (0.35) KMT2ALMNAALDH1A1TSHR
SCHEMBL8734839 0.80 LMNA (0.30) LMNAPKM
SCHEMBL9715139 0.79 SLC40A1 (0.35) SLC40A1KMT2ANR3C1CCR1ESR1
SCHEMBL8735588 0.79 MEN1 (0.34) KMT2AATMALDH1A1TSHRGAA
SCHEMBL8729862 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed