SCHEMBL27447647

SCHEMBL27447647

Cc1c(Cl)cccc1S(=O)(=O)OCP(=O)(O)O

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.40
HSD11B1 P28845 9/20 0.39
EDNRB P24530 2/20 0.37
EDNRA P25101 2/20 0.37
TP53 P04637 1/20 0.37
CCR4 P51679 1/20 0.36
ALDH1A1 P00352 1/20 0.35
SLC40A1 Q9NP59 1/20 0.35
MAPT P10636 1/20 0.35
LMNA P02545 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8734841 0.84 SMN1; SMN2 (0.41) SMN1; SMN2HSD11B1ALDH1A1LMNAPOLB
SCHEMBL27385499 0.82 SMN1; SMN2 (0.37) SMN1; SMN2TP53LMNA
SCHEMBL8734735 0.80 SMN1; SMN2 (0.46) SMN1; SMN2MAPTLMNAPOLB
SCHEMBL5404356 0.80 HSD11B1 (0.43) HSD11B1EDNRBEDNRATP53CCR4
SCHEMBL8734975 0.79 SMN1; SMN2 (0.40) SMN1; SMN2TP53ALDH1A1SLC40A1LMNA
SCHEMBL27385501 0.79 CTSS (0.36) HSD11B1ALDH1A1
SCHEMBL5742716 0.78 HSD11B1 (0.42) HSD11B1EDNRBEDNRATP53CCR4
SCHEMBL155629 0.78 KMT2A (0.42) HSD11B1ALDH1A1MAPTLMNAPOLB
SCHEMBL4895805 0.77 ALDH1A1 (0.44) ALDH1A1MAPTLMNA
SCHEMBL8764172 0.76 HSD11B1 (0.38) SMN1; SMN2HSD11B1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1066266-A PHOSPHOSULFONATE HERBICIDES ROHM & HAAS (US) 1992-11-18 CN claimed