SCHEMBL8734975

SCHEMBL8734975

Cc1cccc(Cl)c1S(=O)(=O)OCP(=O)(O)O

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.40
SLC40A1 Q9NP59 1/20 0.35
NR3C1 P04150 1/20 0.33
KMT2A Q03164 1/20 0.33
CCR1 P32246 3/20 0.33
ESR1 P03372 1/20 0.33
ATM Q13315 1/20 0.32
TP53 P04637 1/20 0.32
ALDH1A1 P00352 2/20 0.32
LMNA P02545 2/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
MAPK1 P28482 1/20 0.32
HTT P42858 1/20 0.32
TRPM4 Q8TD43 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
TYK2 P29597 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8764044 0.90 SMN1; SMN2 (0.36) SMN1; SMN2SLC40A1NR3C1KMT2ACCR1
SCHEMBL8734735 0.89 SMN1; SMN2 (0.46) SMN1; SMN2KMT2AATMLMNA
SCHEMBL8764539 0.87 ALDH1A1 (0.34) SMN1; SMN2SLC40A1NR3C1KMT2ACCR1
SCHEMBL8764015 0.87 SLC40A1 (0.36) SMN1; SMN2SLC40A1NR3C1KMT2ACCR1
SCHEMBL8763944 0.84 SLC40A1 (0.34) SLC40A1NR3C1KMT2ACCR1ALDH1A1
SCHEMBL8763806 0.83 SLC40A1 (0.36) SLC40A1NR3C1KMT2AESR1ALDH1A1
SCHEMBL8731811 0.82 SMN1; SMN2 (0.37) SMN1; SMN2KMT2A
SCHEMBL8763947 0.82 ESR1 (0.33) SLC40A1NR3C1ESR1ALDH1A1LMNA
SCHEMBL8734627 0.82 SLC40A1 (0.33) SLC40A1NR3C1KMT2AESR1ALDH1A1
SCHEMBL8734903 0.81 SLC40A1 (0.33) SLC40A1NR3C1KMT2AESR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP claimed
EP-0511826-B1 Phosphosulfonate herbicides ROHM & HAAS (US) 1997-07-16 EP claimed
US-5500405-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1996-03-19 US claimed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP claimed
CN-1066266-A PHOSPHOSULFONATE HERBICIDES ROHM & HAAS (US) 1992-11-18 CN claimed
EP-0511826-A2 Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1992-11-04 EP claimed
EP-0699390-B1 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM & HAAS (US) 1998-10-07 EP disclosed
EP-0511826-B1 Phosphosulfonate herbicides ROHM & HAAS (US) 1997-07-16 EP disclosed
US-5500405-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1996-03-19 US disclosed
EP-0699390-A2 Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use ROHM AND HAAS COMPANY (US) 1996-03-06 EP disclosed
US-5272128-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1993-12-21 US disclosed
EP-0511826-A2 Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1992-11-04 EP disclosed