SCHEMBL8764044

SCHEMBL8764044

Cc1cccc(Cl)c1S(=O)(=O)OCP(C)(=O)O

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.36
SLC40A1 Q9NP59 1/20 0.34
NR3C1 P04150 1/20 0.33
KMT2A Q03164 1/20 0.33
CCR1 P32246 3/20 0.32
ESR1 P03372 1/20 0.32
PTGS2 P35354 1/20 0.32
ATM Q13315 1/20 0.31
ALDH1A1 P00352 2/20 0.31
LMNA P02545 2/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
TRPM4 Q8TD43 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
AKR1C3 P42330 1/20 0.31
TYK2 P29597 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8763931 0.91 SMN1; SMN2 (0.40) SMN1; SMN2KMT2AATMLMNA
SCHEMBL8734975 0.90 SMN1; SMN2 (0.40) SMN1; SMN2SLC40A1NR3C1KMT2ACCR1
SCHEMBL8764539 0.86 ALDH1A1 (0.34) SMN1; SMN2SLC40A1NR3C1KMT2ACCR1
SCHEMBL8764015 0.85 SLC40A1 (0.36) SMN1; SMN2SLC40A1NR3C1KMT2ACCR1
SCHEMBL8763944 0.83 SLC40A1 (0.34) SLC40A1NR3C1KMT2ACCR1ALDH1A1
SCHEMBL8763841 0.82 NR1H4 (0.33) SMN1; SMN2KMT2A
SCHEMBL8734903 0.82 SLC40A1 (0.33) SLC40A1NR3C1KMT2AESR1ALDH1A1
SCHEMBL8763806 0.82 SLC40A1 (0.36) SLC40A1NR3C1KMT2AESR1ALDH1A1
SCHEMBL8734645 0.81 NR3C1 (0.35) SMN1; SMN2SLC40A1NR3C1KMT2ALMNA
SCHEMBL8734627 0.81 SLC40A1 (0.33) SLC40A1NR3C1KMT2AESR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0511826-B1 Phosphosulfonate herbicides ROHM & HAAS (US) 1997-07-16 EP claimed
EP-0511826-A2 Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1992-11-04 EP claimed