Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 4/20 | 0.49 |
| ▸ | CTSS | P25774 | 6/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.42 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.42 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.42 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.42 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.42 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.42 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.42 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.42 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.42 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8734217 | 0.86 | REN (0.46) | CTSSCTSKCTSBITGB3ITGA2B | |
| SCHEMBL8734213 | 0.84 | YAP1 (0.47) | CTSSTACR2 | |
| SCHEMBL8736745 | 0.83 | CTSD (0.61) | CTSDCTSSCTSKPSMB11PSMA7 | |
| SCHEMBL8945567 | 0.83 | CTSD (0.53) | CTSDCTSSCTSKCTSBITGB3 | |
| SCHEMBL8945683 | 0.83 | CTSD (0.52) | CTSDCTSSCTSKITGB3ITGA2B | |
| SCHEMBL8945246 | 0.81 | CTSD (0.53) | CTSDITGB3ITGA2BPSMB11PSMA7 | |
| SCHEMBL9095899 | 0.81 | CTSD (0.53) | CTSDITGB3ITGA2BPSMB11PSMA7 | |
| SCHEMBL7423701 | 0.81 | CTSD (0.51) | CTSDCTSSCTSKITGB3ITGA2B | |
| SCHEMBL8041703 | 0.80 | CTSD (0.49) | CTSDCTSSCTSKITGB3ITGA2B | |
| SCHEMBL7807953 | 0.79 | CTSD (0.63) | CTSDCTSSCTSKCTSBCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716973-A | ADMINISTERING DIFLUORO STATONE ANALOGS | MERRELL PHARMACEUTICALS INC. (US) | 1998-02-10 | — | — | US | disclosed |
| US-5559140-A | VIRICIDES | MERRELL PHARMACEUTICALS INC. (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0565631-B1 | ANTI-VIRAL COMPOUNDS | MERRELL PHARMA INC (US) | 1996-09-18 | — | — | EP | disclosed |
| EP-0565631-A1 | ANTI-VIRAL COMPOUNDS. | MERRELL DOW PHARMA (US) | 1993-10-20 | — | — | EP | disclosed |
| WO-1992012123-A1 | ANTI-VIRAL COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-23 | — | — | WO | disclosed |