Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | TACR2 | P21452 | 5/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | HTRA1 | Q92743 | 2/20 | 0.44 |
| ▸ | YAP1 | P46937 | 3/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8735984 | 0.86 | CTSD (0.49) | CTSSCTSBCTSKTACR2ITGB3 | |
| SCHEMBL8041651 | 0.82 | MME (0.47) | CTSSCTSKITGB3ITGA2BMME | |
| SCHEMBL8736216 | 0.82 | CTSD (0.53) | CTSSCTSKITGB3ITGA2BHTRA1 | |
| SCHEMBL8945318 | 0.82 | CTSD (0.46) | CTSSCTSKITGB3ITGA2BHTRA1 | |
| SCHEMBL8945610 | 0.81 | MME (0.45) | CTSSCTSKITGB3ITGA2BMME | |
| SCHEMBL7422223 | 0.80 | ITGB3 (0.45) | CTSSCTSKITGB3ITGA2BMME | |
| SCHEMBL8892233 | 0.80 | ITGB3 (0.50) | CTSSCTSBCTSKITGB3ITGA2B | |
| SCHEMBL7933938 | 0.80 | CTSD (0.47) | RENCTSSCTSBCTSKITGB3 | |
| SCHEMBL8945566 | 0.80 | CTSD (0.47) | RENCTSSCTSBCTSKITGB3 | |
| SCHEMBL8492505 | 0.80 | MME (0.64) | ITGB3ITGA2BMMEACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716973-A | ADMINISTERING DIFLUORO STATONE ANALOGS | MERRELL PHARMACEUTICALS INC. (US) | 1998-02-10 | — | — | US | disclosed |
| US-5559140-A | VIRICIDES | MERRELL PHARMACEUTICALS INC. (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0565631-B1 | ANTI-VIRAL COMPOUNDS | MERRELL PHARMA INC (US) | 1996-09-18 | — | — | EP | disclosed |
| EP-0565631-A1 | ANTI-VIRAL COMPOUNDS. | MERRELL DOW PHARMA (US) | 1993-10-20 | — | — | EP | disclosed |
| WO-1992012123-A1 | ANTI-VIRAL COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-23 | — | — | WO | disclosed |