SCHEMBL8739874

SCHEMBL8739874

Cc1ccc2c(c1)c1cc(C)ccc1n2-c1cccc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
ATM Q13315 1/20 0.53
MAPT P10636 4/20 0.41
HTT P42858 3/20 0.41
LMNA P02545 3/20 0.41
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
NR1I2 O75469 1/20 0.41
AHR P35869 1/20 0.41
PGR P06401 1/20 0.40
RORA P35398 1/20 0.40
RORC P51449 1/20 0.40
RORB Q92753 1/20 0.40
FGFR1 P11362 1/20 0.39
ALDH1A1 P00352 3/20 0.38
HPGD P15428 2/20 0.38
HSD17B10 Q99714 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8739863 1.00 KDM4E (0.53) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL8739855 1.00 KDM4E (0.53) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL27058849 0.97 KDM4E (0.50) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL12799780 0.95 L3MBTL1 (0.52) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL14407575 0.93 KDM4E (0.52) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL14407596 0.93 KDM4E (0.52) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL8282722 0.93 MEN1 (0.41) KDM4EL3MBTL1ATMMAPTLMNA
SCHEMBL17691710 0.92 KDM4E (0.55) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL8739859 0.92 KDM4E (0.48) KDM4EL3MBTL1ATMMAPTHTT
SCHEMBL20967606 0.92 L3MBTL1 (0.48) KDM4EL3MBTL1ATMMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11177450-B2 Organoelectroluminescent element, and light emission device, display device, and illumination device in which said organoelectroluminescent element is used UDC IRELAND LIMITED (IE) 2021-11-16 US disclosed
US-10944061-B2 Organic electroluminescent element and compound UDC IRELAND LIMITED (IE) 2021-03-09 US disclosed
US-10243153-B2 Material for organic electroluminescence device and organic electroluminescence device UDC IRELAND LIMITED (IE) 2019-03-26 US disclosed
US-20160254462-A1 Material For Organic Electroluminescence Device And Organic Electroluminescence Device UDC IRELAND LTD (IE) 2016-09-01 US disclosed
US-20160254462-A1 Material For Organic Electroluminescence Device And Organic Electroluminescence Device UDC IRELAND LTD (IE) 2016-09-01 US disclosed
US-9340728-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2016-05-17 US disclosed
US-9340728-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2016-05-17 US disclosed
US-9318714-B2 Material for organic electroluminescence device and organic electroluminescence device UDC Ireland (IE) 2016-04-19 US disclosed
US-9318714-B2 Material for organic electroluminescence device and organic electroluminescence device UDC Ireland (IE) 2016-04-19 US disclosed
US-9193747-B2 Organic electroluminescent device UDC IRELAND LIMITED (IE) 2015-11-24 US disclosed
US-20120126690-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION 2012-05-24 US disclosed
US-20120126690-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION 2012-05-24 US disclosed
US-20110073848-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110073848-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110050092-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
US-20110050092-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
US-20110049497-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
US-20110049497-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE NDUFS3, NDUFS2, NDUFS4 KDM4E 2299/4885L3MBTL1 963/4885ATM 3234/4885
US-20110073848-A1 ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, CYBA, EPCAM KDM4E 2517/4885L3MBTL1 336/4885ATM 3276/4885
US-10944061-B2 Organic electroluminescent element and compound POU2F2, DDT, LEF1 KDM4E 1349/4885L3MBTL1 212/4885ATM 3192/4885
US-20110050092-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTROLUMINESCENCE DEVICE L1CAM, EED, CCNE2 KDM4E 1715/4885L3MBTL1 916/4885ATM 2067/4885
US-20160254462-A1 Material For Organic Electroluminescence Device And Organic Electroluminescence Device VCL, L1CAM, EML4 KDM4E 374/4885L3MBTL1 342/4885ATM 1530/4885
US-10243153-B2 Material for organic electroluminescence device and organic electroluminescence device VCL, L1CAM, EML4 KDM4E 374/4885L3MBTL1 342/4885ATM 1530/4885
US-20110049497-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE VCL, L1CAM, EML4 KDM4E 374/4885L3MBTL1 342/4885ATM 1530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.