SCHEMBL8739870

SCHEMBL8739870

CC(C)c1ccc2c(c1)c1ccccc1n2-c1cccc(-n2c3ccccc3c3cc(C(C)C)ccc32)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
ATM Q13315 1/20 0.48
RORA P35398 1/20 0.44
RORC P51449 1/20 0.44
RORB Q92753 1/20 0.44
PPARG P37231 3/20 0.43
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
KIF11 P52732 1/20 0.39
NOTUM Q6P988 1/20 0.38
PTPN1 P18031 1/20 0.35
ALDH1A1 P00352 3/20 0.35
HPGD P15428 3/20 0.35
MAPT P10636 2/20 0.35
HTT P42858 2/20 0.35
HSD17B10 Q99714 2/20 0.35
NPY5R Q15761 1/20 0.35
GPR3 P46089 1/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13488576 1.00 KDM4E (0.48) KDM4EL3MBTL1ATMRORARORC
SCHEMBL1102407 0.92 KDM4E (0.60) KDM4EL3MBTL1ATMRORARORC
SCHEMBL22260172 0.91 KDM4E (0.55) KDM4EL3MBTL1ATMRORARORC
SCHEMBL26048432 0.90 ATM (0.46) KDM4EL3MBTL1ATMRORARORC
SCHEMBL15496383 0.88 KDM4E (0.53) KDM4EL3MBTL1ATMRORARORC
SCHEMBL24163795 0.88 RORA (0.45) KDM4EL3MBTL1ATMRORARORC
SCHEMBL19342645 0.87 KDM4E (0.48) KDM4EL3MBTL1ATMRORARORC
SCHEMBL13522722 0.86 KDM4E (0.50) KDM4EL3MBTL1ATMRORARORC
SCHEMBL21249247 0.86 KDM4E (0.53) KDM4EL3MBTL1ATMRORARORC
SCHEMBL21376869 0.86 RORA (0.41) KDM4EL3MBTL1ATMRORARORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11177450-B2 Organoelectroluminescent element, and light emission device, display device, and illumination device in which said organoelectroluminescent element is used UDC IRELAND LIMITED (IE) 2021-11-16 US disclosed
US-10944061-B2 Organic electroluminescent element and compound UDC IRELAND LIMITED (IE) 2021-03-09 US disclosed
US-10243153-B2 Material for organic electroluminescence device and organic electroluminescence device UDC IRELAND LIMITED (IE) 2019-03-26 US disclosed
US-20160254462-A1 Material For Organic Electroluminescence Device And Organic Electroluminescence Device UDC IRELAND LTD (IE) 2016-09-01 US disclosed
US-20160254462-A1 Material For Organic Electroluminescence Device And Organic Electroluminescence Device UDC IRELAND LTD (IE) 2016-09-01 US disclosed
US-9340728-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2016-05-17 US disclosed
US-9340728-B2 Organic electroluminescence device UDC IRELAND LIMITED (IE) 2016-05-17 US disclosed
US-9318714-B2 Material for organic electroluminescence device and organic electroluminescence device UDC Ireland (IE) 2016-04-19 US disclosed
US-9318714-B2 Material for organic electroluminescence device and organic electroluminescence device UDC Ireland (IE) 2016-04-19 US disclosed
US-9193747-B2 Organic electroluminescent device UDC IRELAND LIMITED (IE) 2015-11-24 US disclosed
US-20110073848-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110073848-A1 ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110050092-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
US-20110050092-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
WO-2011025068-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 WO disclosed
US-20110049497-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
US-20110049497-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
WO-2011024733-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 WO disclosed
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE NDUFS3, NDUFS2, NDUFS4 KDM4E 2299/4885L3MBTL1 963/4885ATM 3234/4885
US-20110073848-A1 ORGANIC ELECTROLUMINESCENCE DEVICE L1CAM, CYBA, EPCAM KDM4E 2517/4885L3MBTL1 336/4885ATM 3276/4885
US-10944061-B2 Organic electroluminescent element and compound POU2F2, DDT, LEF1 KDM4E 1349/4885L3MBTL1 212/4885ATM 3192/4885
US-20110050092-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTROLUMINESCENCE DEVICE L1CAM, EED, CCNE2 KDM4E 1715/4885L3MBTL1 916/4885ATM 2067/4885
US-20160254462-A1 Material For Organic Electroluminescence Device And Organic Electroluminescence Device VCL, L1CAM, EML4 KDM4E 374/4885L3MBTL1 342/4885ATM 1530/4885
US-10243153-B2 Material for organic electroluminescence device and organic electroluminescence device VCL, L1CAM, EML4 KDM4E 374/4885L3MBTL1 342/4885ATM 1530/4885
US-20110049497-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE VCL, L1CAM, EML4 KDM4E 374/4885L3MBTL1 342/4885ATM 1530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.