SCHEMBL8739898

SCHEMBL8739898

CC(C)(C)c1ccc2c(c1)c1ccccc1n2-c1cccc(-c2cccc(-n3c4ccccc4c4ccccc43)c2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
KIF11 P52732 4/20 0.41
PGR P06401 1/20 0.40
RORA P35398 1/20 0.40
RORC P51449 1/20 0.40
RORB Q92753 1/20 0.40
PPARG P37231 3/20 0.38
OPRD1 P41143 3/20 0.37
KMT2A Q03164 1/20 0.36
PPARA Q07869 1/20 0.36
NOTUM Q6P988 1/20 0.36
ALDH1A1 P00352 2/20 0.36
MAPT P10636 2/20 0.36
MAPK1 P28482 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
SERPINE1 P05121 1/20 0.35
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8739892 1.00 KDM4E (0.46) KDM4EATML3MBTL1KIF11PGR
SCHEMBL8282702 1.00 KDM4E (0.46) KDM4EATML3MBTL1KIF11PGR
SCHEMBL12454691 0.97 KDM4E (0.43) KDM4EATML3MBTL1KIF11PGR
SCHEMBL25708777 0.97 ATM (0.47) KDM4EATML3MBTL1KIF11PGR
SCHEMBL10090552 0.97 KDM4E (0.43) KDM4EATML3MBTL1KIF11PGR
SCHEMBL13232650 0.96 KDM4E (0.42) KDM4EATML3MBTL1KIF11PGR
SCHEMBL18352577 0.96 KDM4E (0.42) KDM4EATML3MBTL1KIF11PGR
SCHEMBL13232668 0.96 KDM4E (0.42) KDM4EATML3MBTL1KIF11PGR
SCHEMBL30322806 0.96 KDM4E (0.42) KDM4EATML3MBTL1KIF11PGR
SCHEMBL10090526 0.96 KDM4E (0.42) KDM4EATML3MBTL1KIF11PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3389110-B1 ORGANIC ELECTROLUMINESCENT ELEMENT UDC IRELAND LTD (IE) 2023-12-27 EP disclosed
US-11177450-B2 Organoelectroluminescent element, and light emission device, display device, and illumination device in which said organoelectroluminescent element is used UDC IRELAND LIMITED (IE) 2021-11-16 US disclosed
US-10944061-B2 Organic electroluminescent element and compound UDC IRELAND LIMITED (IE) 2021-03-09 US disclosed
US-10804469-B2 Charge transport material, organic electroluminescent element, and illumination device, display device, or light-emitting device characterized by using said element UDC IRELAND LIMITED (IE) 2020-10-13 US disclosed
US-10243153-B2 Material for organic electroluminescence device and organic electroluminescence device UDC IRELAND LIMITED (IE) 2019-03-26 US disclosed
US-9935275-B2 Organic electroluminescence device and method for producing the same UDC IRELAND LIMITED (IE) 2018-04-03 US disclosed
US-9935275-B2 Organic electroluminescence device and method for producing the same UDC IRELAND LIMITED (IE) 2018-04-03 US disclosed
EP-2549837-B1 METHOD FOR PRODUCING ORGANIC ELECTROLUMINESCENCE ELEMENT UDC IRELAND LTD (IE) 2018-02-07 EP disclosed
US-20170170410-A1 Organic Electroluminescence Device And Method For Producing The Same UDC IRELAND LTD (IE) 2017-06-15 US disclosed
US-20170170410-A1 Organic Electroluminescence Device And Method For Producing The Same UDC IRELAND LTD (IE) 2017-06-15 US disclosed
WO-2011025068-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 WO disclosed
US-20110050092-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
US-20110050092-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
US-20110049497-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
US-20110049497-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 US disclosed
WO-2011024733-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE FUJIFILM CORPORATION (JP) 2011-03-03 WO disclosed
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed
US-20100171418-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed
US-20100171418-A1 ORGANIC ELECTROLUMINESCENT DEVICE FUJIFILM CORPORATION (JP) 2010-07-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100171111-A1 ORGANIC ELECTROLUMINESCENT DEVICE NDUFS3, NDUFS2, NDUFS4 KDM4E 2299/4885ATM 3234/4885L3MBTL1 963/4885
US-10944061-B2 Organic electroluminescent element and compound POU2F2, DDT, LEF1 KDM4E 1349/4885ATM 3192/4885L3MBTL1 212/4885
US-20110050092-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTROLUMINESCENCE DEVICE L1CAM, EED, CCNE2 KDM4E 1715/4885ATM 2067/4885L3MBTL1 916/4885
US-10804469-B2 Charge transport material, organic electroluminescent element, and illumination device, display device, or light-emitting device characterized by using said element ITGAL, ITGA1, ITGB1 KDM4E 3242/4885ATM 3137/4885L3MBTL1 250/4885
US-10243153-B2 Material for organic electroluminescence device and organic electroluminescence device VCL, L1CAM, EML4 KDM4E 374/4885ATM 1530/4885L3MBTL1 342/4885
US-20110049497-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE AND ORGANIC ELECTROLUMINESCENCE DEVICE VCL, L1CAM, EML4 KDM4E 374/4885ATM 1530/4885L3MBTL1 342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.