Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | GAA | P10253 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | CDC7 | O00311 | 2/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873941 | 0.89 | RAB9A (0.48) | RAB9AKDM4EGAANPC1ALDH1A1 | |
| SCHEMBL882714 | 0.81 | MAPT (0.57) | KDM4EALDH1A1MAPTHPGDCDC7 | |
| SCHEMBL874730 | 0.80 | NPC1 (0.39) | RAB9AKDM4EGAANPC1ALDH1A1 | |
| SCHEMBL874785 | 0.78 | SMN1; SMN2 (0.41) | RAB9AKDM4EGAANPC1ALDH1A1 | |
| SCHEMBL874301 | 0.76 | ALDH1A1 (0.40) | RAB9ANPC1ALDH1A1MAPTHPGD | |
| SCHEMBL16703796 | 0.75 | SMN1; SMN2 (0.49) | RAB9AKDM4EGAANPC1ALDH1A1 | |
| SCHEMBL8341574 | 0.75 | SMN1; SMN2 (0.64) | RAB9AKDM4EGAANPC1ALDH1A1 | |
| SCHEMBL8338941 | 0.75 | ALDH1A1 (0.54) | RAB9AKDM4EGAANPC1ALDH1A1 | |
| SCHEMBL14018508 | 0.75 | RAB9A (0.77) | RAB9AKDM4EGAANPC1ALDH1A1 | |
| SCHEMBL4497703 | 0.75 | SMN1; SMN2 (0.59) | RAB9AKDM4EGAANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038905-A1 | THIENOPYRIDINE NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012038905-A1 | THIENOPYRIDINE NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |