Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.42 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.36 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432291 | 0.83 | ADORA2A (0.41) | SQORMAPK1LMNAMAPTADORA2A | |
| SCHEMBL27684707 | 0.81 | HDAC8 (0.39) | CCNCCDK8PIK3CDPIK3CAPIK3CB | |
| SCHEMBL8744832 | 0.80 | MCL1 (0.42) | SQORMAPK1MAPTADORA2AADORA1 | |
| SCHEMBL8744743 | 0.80 | MCL1 (0.41) | SQORLMNAMAPTADORA2AADORA1 | |
| SCHEMBL8744752 | 0.80 | ERBB2 (0.41) | LMNAMAPTADORA2AADORA1XDH | |
| SCHEMBL8744687 | 0.80 | KIF11 (0.47) | — | |
| SCHEMBL8744692 | 0.76 | CYP2A6 (0.43) | LMNAMAPTNPC1CYP1A2CYP3A4 | |
| SCHEMBL4874412 | 0.75 | LMNA (0.40) | CCNCCDK8MAPK1IDO1LMNA | |
| SCHEMBL9876232 | 0.74 | MAPT (0.43) | PIK3CAPIK3CBMAPTXDHNPC1 | |
| SCHEMBL8744753 | 0.73 | CTSS (0.49) | IDO1MAPTADORA2AADORA1XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653421-B1 | Process for preparing 2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA (JP) | 1997-01-15 | — | — | EP | disclosed |
| US-5552557-A | Process for preparing 2-cyanoimidazole compounds by reaction of an amino ketone compound | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1996-09-03 | — | — | US | disclosed |
| EP-0653421-A1 | Process for preparing 2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |