Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | GPR183 | P32249 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745257 | 0.87 | TNNC1 (0.35) | MAOBTLR4ALDH1A1MEN1MAPT | |
| SCHEMBL8745626 | 0.87 | TRPA1 (0.35) | MAOBTLR4 | |
| SCHEMBL8745253 | 0.86 | MAOA (0.40) | MAOBTLR4GPR183CYP2C9 | |
| SCHEMBL9135731 | 0.85 | MAOB (0.39) | MAOBCYP1A2CHRNA7 | |
| SCHEMBL8745226 | 0.83 | MAOB (0.39) | MAOBALDH1A1 | |
| SCHEMBL8745280 | 0.82 | TNNC1 (0.45) | ALDH1A1KDM4ECYP2C9LMNA | |
| SCHEMBL13126444 | 0.82 | MAOB (0.47) | MAOBTLR4GPR183ALDH1A1MEN1 | |
| SCHEMBL8745194 | 0.82 | TNNC1 (0.37) | MAOBALDH1A1MEN1POLBMAPT | |
| SCHEMBL8745161 | 0.82 | NFE2L2 (0.38) | MAOB | |
| SCHEMBL9137050 | 0.81 | GRIK1 (0.37) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563981-B1 | Cis-1,4-substituted 2-butene derivative | CHISSO CORP (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5401434-A | Cis-1,4-substituted 2-butene derivative | CHISSO CORPORATION (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0563981-A2 | Cis-1,4-substituted 2-butene derivative | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |